The average time from the onset until clinical recovery for simple cases is approximately 2 weeks and 3 to 6 weeks for patients with acute disease.
The clinical progression is divided into different stages: 1
- Week one is characterized by fever, muscle pain and other systemic symptoms that generally improve within a few days. 2,3
- As the disease progresses, in week two patients frequently have a recurring fever, diarrhea and oxygen desaturation.3
In between day 10 and 15 a severe clinical worsening can be produced and progress to stage three, characterized by SDRA (Acute Respiratory Difficulty Syndrome) and will require a ventilator.3